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Cellosaurus C-HC-4 (CVCL_W519)

[Text version]
Cell line name C-HC-4
Synonyms c-Hc-4; C-Hc4; cHc4; CHC4; HC-4; Hc-4
Accession CVCL_W519
Resource Identification Initiative To cite this cell line use: C-HC-4 (RRID:CVCL_W519)
Comments Population: Japanese.
Doubling time: ~20 hours (PubMed=2856442).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): TKG=TKG 0733

Markers:
AmelogeninX
CSF1PO13
D5S81810
D7S82010,12
D13S31711
D16S5399
TH016,9
TPOX9
vWA14,18

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Publications

PubMed=6300668; DOI=10.1016/0027-5107(83)90097-0
Syuiti Abe, Nobuo Nemoto, Motomichi Sasaki;
Sister-chromatid exchange induction by indirect mutagens/carcinogens, aryl hydrocarbon hydroxylase activity and benzo[alpha]pyrene metabolism in cultured human hepatoma cells.
Mutat. Res. 109:83-90(1983)

PubMed=2856442
Fumiaki Sasaki, Hiroshi Kameda, Yoshinobu Hata, Junichi Uchino;
Establishment of the human hepatocellular carcinoma cell line and its characteristics.
Hum. Cell 1:89-91(1988)

PubMed=2543326
Yoshinobu Hata, Motomu Igarashi, Naoyuki Takada, Tsutomu Namieno, Fumiaki Sasaki, Yoshie Une, Junichi Uchino, Masaharu Kajiwara;
Development of a new therapeutic method in hepatocellular carcinoma using a culture system -- the intensifying effect of human epidermal growth factor (hEGF) on the antitumor action of antitumor agents.
Gan To Kagaku Ryoho 16:1874-1879(1989)

PubMed=7874267; DOI=10.1007/BF02349278
Shigeo Ikuta, Fumio Itoh, Yuji Hinoda, Minoru Toyota, Yusuke Makiguchi, Kohzoh Imai, Akira Yachi;
Expression of cytoskeletal-associated protein tyrosine phosphatase PTPH1 mRNA in human hepatocellular carcinoma.
J. Gastroenterol. 29:727-732(1994)

PubMed=12029633; DOI=10.1053/jhep.2002.33683
Kohichiroh Yasui, Shigeki Arii, Chen Zhao, Issei Imoto, Masakazu Ueda, Hisaki Nagai, Mitsuru Emi, Johji Inazawa;
TFDP1, CUL4A, and CDC16 identified as targets for amplification at 13q34 in hepatocellular carcinomas.
Hepatology 35:1476-1484(2002)

Cross-references
Cell line collections (Providers) TKG; TKG 0733
Cell line databases/resources CGH-DB; 9073-4
Chemistry resources ChEMBL-Cells; CHEMBL4523518
ChEMBL-Targets; CHEMBL4523549
PubChem_Cell_line; CVCL_W519
Encyclopedic resources Wikidata; Q54799760
Entry history
Entry creation16-Apr-2014
Last entry update02-May-2024
Version number13