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Cellosaurus KAO (CVCL_W455)

[Text version]
Cell line name KAO
Synonyms Kao
Accession CVCL_W455
Resource Identification Initiative To cite this cell line use: KAO (RRID:CVCL_W455)
Comments Population: Japanese.
Doubling time: ~34 hours (PubMed=9247632).
Omics: Transcriptomics; Microarray.
Anecdotal: Cell line name derived from the first name (Kaori) of the patient.
Sequence variations
  • Gene fusion; HGNC; HGNC:783; ATF1 + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ATF1, EWS-ATF; Note=Type 1: EWSR1 exon 8 fused to ATF1 exon 4 (PubMed=15150091).
Disease Clear cell sarcoma of soft tissue (NCIt: C3745)
Soft tissue sarcoma (ORDO: Orphanet_3394)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=9247632; DOI=10.1007/s004280050068
Hiroaki Hiraga, Takayuki Nojima, Syuiti Abe, Katsushige Yamashiro, Shinya Yamawaki, Kiyoshi Kaneda, Kazuo Nagashima;
Establishment of a new continuous clear cell sarcoma cell line Morphological and cytogenetic characterization and detection of chimaeric EWS/ATF-1 transcripts.
Virchows Arch. 431:45-51(1997)

PubMed=12966428; DOI=10.1038/sj.bjc.6601212; PMCID=PMC2376962
Kim K.C. Li, Jane Goodall, Colin Ronald Goding, Shuen-Kuei Liao, Cheng-Hsu Wang, Y.-C. Lin, Hiroaki Hiraga, Takayuki Nojima, Kazuo Nagashima, Karl-Ludwig Schaefer, Kevin A.W. Lee;
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma.
Br. J. Cancer 89:1072-1078(2003)

PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809
Karl-Ludwig Schaefer, Kristin Brachwitz, Daniel H. Wai, Yvonne Braun, Raihanatou Diallo, Eberhard Korsching, Martin Eisenacher, Reinhard Voss, Frans van Valen, Claudia Baer, Barbara Selle ...Show all 18 authors... , Laura Spahn, Shuen-Kuei Liao, Kevin A.W. Lee, Pancras Cornelis Wilhelmus Hogendoorn, Guido Reifenberger, Helmut Erich Gabbert, Christopher Poremba; Show fewer authors
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Cancer Res. 64:3395-3405(2004)

Cross-references
Encyclopedic resources Wikidata; Q54899470
Polymorphism and mutation databases Cosmic; 1093167
Entry history
Entry creation16-Apr-2014
Last entry update10-Apr-2025
Version number14