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Cellosaurus UM-3 [Human plasma cell myeloma] (CVCL_W394)

[Text version]
Cell line name UM-3 [Human plasma cell myeloma]
Synonyms UM3
Accession CVCL_W394
Resource Identification Initiative To cite this cell line use: UM-3 [Human plasma cell myeloma] (RRID:CVCL_W394)
Comments Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10087940; DOI=10.1016/S0165-4608(98)00157-5
Jeroen Kuipers, Jan Willem Vaandrager, Danielle Olde Weghuis, Peter Lees Pearson, Jacques Scheres, Henk Martinus Lokhorst, Hans Cornelius Clevers, Bert J.E.G. Bast;
Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines.
Cancer Genet. Cytogenet. 109:99-107(1999)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=15257707; DOI=10.1111/j.1365-2141.2004.05050.x
Gienke R. Boersma-Vreugdenhil, Jeroen Kuipers, Esther van Stralen, Ton Peeters, Lucienne Michaux, Anne Hagemeijer, Peter Lees Pearson, Hans Cornelius Clevers, Bert J.E.G. Bast;
The recurrent translocation t(14;20)(q32;q12) in multiple myeloma results in aberrant expression of MAFB: a molecular and genetic analysis of the chromosomal breakpoint.
Br. J. Haematol. 126:355-363(2004)

Cross-references
Encyclopedic resources Wikidata; Q54990753
Entry history
Entry creation16-Apr-2014
Last entry update14-Aug-2025
Version number12