Cellosaurus TWNT-4 (CVCL_W296)
| Cell line name | TWNT-4 |
|---|---|
| Synonyms | TWNT4 |
| Accession | CVCL_W296 |
| Resource Identification Initiative | To cite this cell line use: TWNT-4 (RRID:CVCL_W296) |
| Comments | Population: Japanese. Characteristics: Because it has been transduced by a construct containing LoxP sites, transfection with the Cre recombinase eliminates the TERT gene thus reverting the cells to a non-immortal phenotype. Characteristics: Transduced with a retroviral vector SSR#197 (MoMLV/LTR-LoxP-hTERT-IRES-EGFP-LoxP-MoMLV/LTR) expressing hTERT and eGFP flanked by a pair of loxP sites. Genetic integration: Method=Transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Derived from site: In situ; Liver; UBERON=UBERON_0002107. Cell type: Hepatic stellate cell; CL=CL_0000632. |
| Disease | Epithelioid hemangioendothelioma (NCIt: C3800) Epithelioid hemangioendothelioma (ORDO: Orphanet_157791) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0390 (LI90) |
| Sex of cell | Female |
| Age at sampling | 55Y |
| Category | Telomerase immortalized cell line |
| Publications | PubMed=12953924; DOI=10.3727/000000003108747064 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54973429 |
| Entry history | |
| Entry creation | 16-Apr-2014 |
| Last entry update | 10-Apr-2025 |
| Version number | 15 |