Cellosaurus cell line 136-2 (CVCL

Cross-references
Cell line name	136-2
Accession	CVCL_W281
Resource Identification Initiative	To cite this cell line use: 136-2 (RRID:CVCL_W281)
Comments	Derived from site: Metastatic; Not specified.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Arg (c.737T>G); ClinVar=VCV000127822; Zygosity=Unspecified (PubMed=10070891).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=3402430; DOI=10.1002/j.1460-2075.1988.tb02909.x; PMCID=PMC454430 Rogier Versteeg, Inge A. Noordermeer, Margreet Kruse-Wolters, Dirk J. Ruiter, Peter I. Schrier; c-myc down-regulates class I HLA expression in human melanomas. EMBO J. 7:1023-1029(1988) PubMed=10070891; DOI=10.1038/sj.bjc.6690147; PMCID=PMC2362648 Shuraila Francisca Zerp, Andrea van Elsas, Lucy T.C. Peltenburg, Peter I. Schrier; p53 mutations in human cutaneous melanoma correlate with sun exposure but are not always involved in melanomagenesis. Br. J. Cancer 79:921-926(1999)
Cell line databases/resources	cancercelllines; CVCL_W281
Encyclopedic resources	Wikidata; Q54581655
Polymorphism and mutation databases	Cosmic; 1418452 IARC_TP53; 10953
Entry history
Entry creation	16-Apr-2014
Last entry update	19-Dec-2024
Version number	11