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Cellosaurus SPC-A1/DTX (CVCL_W217)

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Cell line name SPC-A1/DTX
Synonyms SPC-A1/docetaxel
Accession CVCL_W217
Resource Identification Initiative To cite this cell line use: SPC-A1/DTX (RRID:CVCL_W217)
Comments Problematic cell line: Contaminated. Parent cell line (SPC-A1) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6955 (SPC-A1)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=22460125; DOI=10.2119/molmed.2011.00230; PMCID=PMC3409275
Rui Wang, Jia-Yuan Huang, Bing Feng, Wei De, Long-Bang Chen;
Identification of ING4 (inhibitor of growth 4) as a modulator of docetaxel sensitivity in human lung adenocarcinoma.
Mol. Med. 18:874-886(2012)

PubMed=23035364; DOI=10.3727/096504012X13425470196218
Hai-Zhu Song, Jun Yi, Jing Chen, Long-Bang Chen;
Nimotuzumab increases chemosensitivity of human lung adenocarcinoma cell lines to docetaxel.
Oncol. Res. 20:39-47(2012)

Cross-references
Encyclopedic resources Wikidata; Q54955523
Entry history
Entry creation16-Apr-2014
Last entry update10-Apr-2025
Version number11