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Cellosaurus LK1 [Human ovarian carcinoma] (CVCL_W131)

[Text version]
Cell line name LK1 [Human ovarian carcinoma]
Synonyms LK-1
Accession CVCL_W131
Resource Identification Initiative To cite this cell line use: LK1 [Human ovarian carcinoma] (RRID:CVCL_W131)
Comments Microsatellite instability: Stable (MSS) (PubMed=15677628).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
Disease Ovarian carcinoma (NCIt: C4908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=1892748; DOI=10.1038/bjc.1991.279; PMCID=PMC1977519
Prakash Mistry, Lloyd R. Kelland, George Abel, Sanjiv Sidhar, Kenneth Reginald Harrap;
The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.
Br. J. Cancer 64:215-220(1991)

PubMed=12068308; DOI=10.1038/nature00766
Helen R. Davies, Graham Robert Bignell, Charles Cox, Philip J. Stephens, Sarah Edkins, Sheila Clegg, Jon W. Teague, Hayley Woffendin, Mathew J. Garnett, William Bottomley, Neil Davis ...Show all 52 authors... , Ed Dicks, Rebecca Ewing, Yvonne Floyd, Kristian Gray, Sarah Hall, Rachel Hawes, Jaime Hughes, Vivian Kosmidou, Andrew Menzies, Catherine Mould, Adrian Parker, Claire Stevens, Stephen Watt, Steven Hooper, Rebecca Wilson, Hiran Jayatilake, Barry Austin Gusterson, Colin S. Cooper, Janet M. Shipley, Darren Hargrave, Kathy Pritchard-Jones, Norman J. Maitland, Georgia Chenevix-Trench, Gregory J. Riggins, Darell Doty Bigner, Giuseppe Palmieri, Antonio Cossu, Adrienne M. Flanagan, Andrew Nicholson, Judy W.C. Ho, Suet Yi Leung, Siu Tsan Yuen, Barbara L. Weber, Hilliard Foster Seigler, Timothy L. Darrow, Hugh F. Paterson, Richard Marais, Christopher John Marshall, Richard Wooster, Michael Rudolf Stratton, P. Andrew Futreal; Show fewer authors
Mutations of the BRAF gene in human cancer.
Nature 417:949-954(2002)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Kylie Louise Gorringe, Suet-Feung Chin, Paul D.P. Pharoah, Joanne M. Staines, Carla Oliveira, Paul A.W. Edwards, Carlos Caldas;
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W131
Encyclopedic resources Wikidata; Q54902669
Gene expression databases GEO; GSM313698
Polymorphism and mutation databases Cosmic; 724832
Cosmic; 1609534
Progenetix; CVCL_W131
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number14