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Cellosaurus O24B (CVCL_W083)

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Cell line name O24B
Accession CVCL_W083
Resource Identification Initiative To cite this cell line use: O24B (RRID:CVCL_W083)
Comments Omics: Variations; SNP array analysis.
Sequence variations
  • Mutation; HGNC; HGNC:950; BAP1; Simple; p.Gln322fs*9 (c.966_978del13); Zygosity=Homozygous (PubMed=21642991).
Disease Pleural malignant mesothelioma (NCIt: C7376)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=21642991; DOI=10.1038/ng.855; PMCID=PMC4643098
Matthew J. Bott, Marie Brevet, Barry Stephen Taylor, Shigeki Shimizu, Tatsuo Ito, Lu Wang, Jenette Creaney, Richard A. Lake, Maureen F. Zakowski, Boris A. Reva, Chris Sander ...Show all 18 authors... , Robert Delsite, Simon N. Powell, Qin Zhou, Rong-Lai Shen, Adam B. Olshen, Valerie W. Rusch, Marc Ladanyi; Show fewer authors
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Nat. Genet. 43:668-672(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W083
Biological sample resources BioSamples; SAMEA100789
Encyclopedic resources Wikidata; Q54931663
Gene expression databases GEO; GSM726280
Polymorphism and mutation databases Cosmic; 1522767
Progenetix; CVCL_W083
Entry history
Entry creation16-Apr-2014
Last entry update10-Apr-2025
Version number14