• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=22850568).
  

PubMed=20099279; DOI=10.1002/ijc.25182
Olga Kholmanskikh, Nicolas van Baren, Francis Brasseur, Sabrina Ottaviani, Julie Vanacker, Nathalie Arts, Pierre van der Bruggen, Pierre G. Coulie, Etienne De Plaen;
Interleukins 1alpha and 1beta secreted by some melanoma cell lines strongly reduce expression of MITF-M and melanocyte differentiation antigens.
Int. J. Cancer 127:1625-1636(2010)

PubMed=22850568; DOI=10.1158/1078-0432.CCR-12-1632; PMCID=PMC3463754
Jahan S. Khalili, Shu-Juan Liu, Tania G. Rodriguez-Cruz, Mayra Whittington, Seth Wardell, Cheng-Wen Liu, Min-Ying Zhang, Zachary A. Cooper, Dennie T. Frederick, Yu-Feng Li, Min Zhang ...Show all 21 authors... , Richard W. Joseph, Chantale Bernatchez, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Laszlo G. Radvanyi, Richard E. Davis, Michael A. Davies, Jennifer A. Wargo, Patrick Hwu, Gregory A. Lizee; Show fewer authors
Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma.
Clin. Cancer Res. 18:5329-5340(2012)