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Cellosaurus LEC14 (CVCL_VU62)

[Text version]

Cell line name LEC14
Synonyms CHO-LEC14; Pro-LEC14.4A
Accession CVCL_VU62
Resource Identification Initiative To cite this cell line use: LEC14 (RRID:CVCL_VU62)
Comments Selected for resistance to: UniProtKB; P02867; Pisum sativum lectin.
Transformant: ChEBI; CHEBI:21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from sampling site: Ovary.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4382 (CHO Pro-5)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line

PubMed=3456174; DOI=10.1007/BF01560727
Ripka J., Stanley P.
Lectin-resistant CHO cells: selection of four new pea lectin-resistant phenotypes.
Somat. Cell Mol. Genet. 12:51-62(1986)

PubMed=8631778; DOI=10.1074/jbc.271.13.7484
Raju T.S., Stanley P.
LEC14, a dominant Chinese hamster ovary glycosylation mutant expresses complex N-glycans with a new N-acetylglucosamine residue in the core region.
J. Biol. Chem. 271:7484-7493(1996)

PubMed=9603907; DOI=10.1074/jbc.273.23.14090
Raju T.S., Stanley P.
Gain-of-function Chinese hamster ovary mutants LEC18 and LEC14 each express a novel N-acetylglucosaminyltransferase activity.
J. Biol. Chem. 273:14090-14098(1998)

Encyclopedic resources Wikidata; Q95982028
Entry history
Entry creation24-May-2019
Last entry update02-Jul-2020
Version number3