Cellosaurus cell line Mel 90.07 (CVCL

Cellosaurus Mel 90.07 (CVCL_VU42)

Cross-references
Cell line name	Mel 90.07
Synonyms	mel90.07; 90.07
Accession	CVCL_VU42
Resource Identification Initiative	To cite this cell line use: Mel 90.07 (RRID:CVCL_VU42)
Comments	From: Leiden University Medical Center; Leiden; Netherlands. Omics: Transcriptomics; RNAseq.
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (PubMed=25728708).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=25502142; DOI=10.1038/ncomms6712; PMCID=PMC4428333 Judith Muller, Oscar Krijgsman, Jennifer Tsoi, Lidia Robert, Willy Hugo, Chunying Song, Xiang-Ju Kong, Patricia Abrao Possik, Paulien D.M. Cornelissen-Steijger, Marnix H. Geukes Foppen, Kristel Kemper ...Show all 19 authors... , Colin Ronald Goding, Ultan McDermott, Christian Blank, John Haanen, Thomas G. Graeber, Antoni Ribas, Roger S. Lo, Daniel S. Peeper; Show fewer authors Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma. Nat. Commun. 5:5712.1-5712.15(2014) PubMed=25728708; DOI=10.1111/pcmr.12364 Celia J. Vogel, Marjon A. Smit, Gianluca Maddalo, Patricia Abrao Possik, Rolf W. Sparidans, Sjoerd Henricus van der Burg, Elizabeth M.E. Verdegaal, Albert J.R. Heck, Ahmed A. Samatar, Jos Heindrik Beijnen, A.F. Maarten Altelaar, Daniel S. Peeper; Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK. Pigment Cell Melanoma Res. 28:307-317(2015)
Cell line databases/resources	cancercelllines; CVCL_VU42
Encyclopedic resources	Wikidata; Q95988494
Gene expression databases	GEO; GSM1507942
Entry history
Entry creation	24-May-2019
Last entry update	14-Aug-2025
Version number	8