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Cellosaurus TERT-hBA (CVCL_VU19)

[Text version]
Cell line name TERT-hBA
Synonyms TERT-immortalized human Brown Adipocyte cell line
Accession CVCL_VU19
Resource Identification Initiative To cite this cell line use: TERT-hBA (RRID:CVCL_VU19)
Comments Characteristics: Recapitulate the gene expression profile of brown adipocytes. UCP1-positive and responsive to beta-adrenergic stimulation.
Doubling time: ~1-2 days (PubMed=28957413).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VU20 ! TERT-hWA
Sex of cell Female
Age at sampling 48Y
Category Telomerase immortalized cell line
Publications

PubMed=28957413; DOI=10.1371/journal.pone.0185624; PMCID=PMC5619805
Lasse K. Markussen, Marie Sophie Lykke Isidor, Peter Breining, Elise S. Andersen, Nanna E. Rasmussen, Louise I. Petersen, Steen B. Pedersen, Bjorn Richelsen, Jacob B. Hansen;
Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor.
PLoS ONE 12:e0185624.1-e0185624.17(2017)

Cross-references
Encyclopedic resources Wikidata; Q98133222
Entry history
Entry creation24-May-2019
Last entry update14-Aug-2025
Version number9