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Cellosaurus WT-1 (CVCL_VU16)

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Cell line name WT-1
Accession CVCL_VU16
Resource Identification Initiative To cite this cell line use: WT-1 (RRID:CVCL_VU16)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348.
Cell type: Preadipocyte; CL=CL_0002334.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: FVB.
Sex of cell Sex unspecified
Age at sampling <1D
Category Transformed cell line
STR profile Source(s): Millipore=SCC255

Markers:
Mouse STR 1-110
Mouse STR 1-213
Mouse STR 2-19
Mouse STR 3-214
Mouse STR 4-219.3,20.3
Mouse STR 5-517
Mouse STR 6-417
Mouse STR 6-712
Mouse STR 7-129
Mouse STR 8-115.3
Mouse STR 11-214
Mouse STR 12-117
Mouse STR 13-115.2,16.2
Mouse STR 15-320.3
Mouse STR 17-212,15
Mouse STR 18-316,18
Mouse STR 19-212,13
Mouse STR X-126

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Publications

PubMed=10574950; DOI=10.1074/jbc.274.49.34795
Johannes Klein, Mathias Fasshauer, Moriko Ito, Bradford Barr Lowell, Manuel Benito, Carl Ronald Kahn;
Beta(3)-adrenergic stimulation differentially inhibits insulin signaling and decreases insulin-induced glucose uptake in brown adipocytes.
J. Biol. Chem. 274:34795-34802(1999)

PubMed=28494871; DOI=10.1016/j.celrep.2017.04.035; PMCID=PMC5637386
Raymond Ng, Nurul Attiqah Hussain, Qiong-Yi Zhang, Cheng-Wei Chang, Hong-Yu Li, Yan-Yun Fu, Lei Cao, Wei-Ping Han, Walter Stunkel, Feng Xu;
miRNA-32 drives brown fat thermogenesis and trans-activates subcutaneous white fat browning in mice.
Cell Rep. 19:1229-1246(2017)

Cross-references
Cell line collections (Providers) Millipore; SCC255
Encyclopedic resources Wikidata; Q98135013
Entry history
Entry creation24-May-2019
Last entry update14-Aug-2025
Version number11