| Cell line name |
HEL69.5 |
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| Accession |
CVCL_VT45 |
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| Resource Identification Initiative |
To cite this cell line use: HEL69.5 (RRID:CVCL_VT45) |
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| Comments |
From: University of Helsinki; Helsinki; Finland.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608. |
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| Sequence variations |
|
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| Disease |
Fragile X syndrome (NCIt: C84717)
Fragile X syndrome (ORDO: Orphanet_908) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Male |
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| Age at sampling |
Children |
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| Category |
Induced pluripotent stem cell |
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| Publications | PubMed=27411166; DOI=10.1002/dneu.22419
Venkat Swaroop Achuta, Heli Grym, Noora Putkonen, Verna Louhivuori, Virve Karkkainen, Jari Koistinaho, Laurent Roybon, Maija L. Castren;
Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome.
Dev. Neurobiol. 77:438-453(2017) PubMed=29339535; DOI=10.1126/scisignal.aan8784
Venkat Swaroop Achuta, Tommi Moykkynen, Ulla-Kaisa Peteri, Giorgio Turconi, Claudio Rivera-Baeza, Kari Pekka Keinanen, Maija L. Castren;
Functional changes of AMPA responses in human induced pluripotent stem cell-derived neural progenitors in fragile X syndrome.
Sci. Signal. 11:eaan8784.1-eaan8784.11(2018) PubMed=30503263; DOI=10.1016/j.stemcr.2018.11.003; PMCID=PMC6294261
Claudia Danesi, Venkat Swaroop Achuta, Padraic Corcoran, Ulla-Kaisa Peteri, Giorgio Turconi, Nobuaki Matsui, Ilyas Albayrak, Veronika Rezov, Anders Isaksson, Maija L. Castren;
Increased calcium influx through L-type calcium channels in human and mouse neural progenitors lacking fragile X mental retardation protein.
Stem Cell Reports 11:1449-1461(2018) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q94096141
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| Entry history |
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| Entry creation | 24-May-2019 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 10 |
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