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Cellosaurus HEL100.2 (CVCL_VT44)

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Cell line name HEL100.2
Accession CVCL_VT44
Resource Identification Initiative To cite this cell line use: HEL100.2 (RRID:CVCL_VT44)
Comments From: University of Helsinki; Helsinki; Finland.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Fragile X syndrome (NCIt: C84717)
Fragile X syndrome (ORDO: Orphanet_908)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VT43 ! HEL100.1
Sex of cell Male
Age at sampling Children
Category Induced pluripotent stem cell
Publications

PubMed=27411166; DOI=10.1002/dneu.22419
Venkat Swaroop Achuta, Heli Grym, Noora Putkonen, Verna Louhivuori, Virve Karkkainen, Jari Koistinaho, Laurent Roybon, Maija L. Castren;
Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome.
Dev. Neurobiol. 77:438-453(2017)

PubMed=29339535; DOI=10.1126/scisignal.aan8784
Venkat Swaroop Achuta, Tommi Moykkynen, Ulla-Kaisa Peteri, Giorgio Turconi, Claudio Rivera-Baeza, Kari Pekka Keinanen, Maija L. Castren;
Functional changes of AMPA responses in human induced pluripotent stem cell-derived neural progenitors in fragile X syndrome.
Sci. Signal. 11:eaan8784.1-eaan8784.11(2018)

PubMed=30503263; DOI=10.1016/j.stemcr.2018.11.003; PMCID=PMC6294261
Claudia Danesi, Venkat Swaroop Achuta, Padraic Corcoran, Ulla-Kaisa Peteri, Giorgio Turconi, Nobuaki Matsui, Ilyas Albayrak, Veronika Rezov, Anders Isaksson, Maija L. Castren;
Increased calcium influx through L-type calcium channels in human and mouse neural progenitors lacking fragile X mental retardation protein.
Stem Cell Reports 11:1449-1461(2018)

Cross-references
Encyclopedic resources Wikidata; Q94096118
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number10