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Cellosaurus QIMR-PB1 (CVCL_VS49)

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Cell line name QIMR-PB1
Synonyms PB1; QIMR-B007
Accession CVCL_VS49
Resource Identification Initiative To cite this cell line use: QIMR-PB1 (RRID:CVCL_VS49)
Comments Doubling time: 79.4 +- 6.3 hours (PubMed=30894629).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain, left frontal lobe; UBERON=UBERON_0002811.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (QCell).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg130Ter (c.388C>T); ClinVar=VCV000007819; Zygosity=Homozygous (QCell).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
STR profile Source(s): PubMed=30894629

Markers:
AmelogeninX,Y
CSF1PO11,13
D5S81810,11
D7S8209,11
D13S31712
D16S53912
D21S1130
TH017,9
TPOX8
vWA17

Run an STR similarity search on this cell line
Web pages Provider; Qcell; -; https://www.qimrberghofer.edu.au/commercial-collaborations/partner-with-us/q-cell/
Publications

PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001
Brett William Stringer, Bryan W. Day, Rochelle C.J. D'Souza, Paul R. Jamieson, Kathleen S. Ensbey, Zara C. Bruce, Yi-Chieh Lim, Kate Goasdoue, Carolin Offenhauser, Seckin Akgul, Suzanne Allan ...Show all 22 authors... , Thomas Robertson, Peter Geoffrey Lucas, Gert Tollesson, Scott Campbell, Craig Winter, Hong-Do Do, Alexander Dobrovic, Po-Ling Inglis, Rosalind L. Jeffree, Terrance Grant Johns, Andrew Wallace Boyd; Show fewer authors
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 9:4902.1-4902.14(2019)

PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897
Brett William Stringer, Bryan W. Day, Rochelle C.J. D'Souza, Paul R. Jamieson, Kathleen S. Ensbey, Zara C. Bruce, Yi-Chieh Lim, Kate Goasdoue, Carolin Offenhauser, Seckin Akgul, Suzanne Allan ...Show all 22 authors... , Thomas Robertson, Peter Geoffrey Lucas, Gert Tollesson, Scott Campbell, Craig Winter, Hong-Do Do, Alexander Dobrovic, Po-Ling Inglis, Rosalind L. Jeffree, Terrance Grant Johns, Andrew Wallace Boyd; Show fewer authors
Publisher correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 10:1185.1-1185.14(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VS49
Encyclopedic resources Wikidata; Q98128766
Gene expression databases GEO; GSM3347675
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number12