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Cellosaurus QIMR-HW1 (CVCL_VS45)

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Cell line name QIMR-HW1
Synonyms HW1; QIMR-B003
Accession CVCL_VS45
Resource Identification Initiative To cite this cell line use: QIMR-HW1 (RRID:CVCL_VS45)
Comments Doubling time: 55.8 +- 2.7 hours (PubMed=30894629).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain, right fronto-parietal lobe.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (QCell).
  • Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Ala289Val (c.866C>T); ClinVar=VCV000376209; Zygosity=Heterozygous (QCell).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): PubMed=30894629

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S8208,10
D13S31712
D16S53913
D21S1128,29
TH016,9
TPOX8
vWA15,18

Run an STR similarity search on this cell line
Web pages Provider; Qcell; -; https://www.qimrberghofer.edu.au/commercial-collaborations/partner-with-us/q-cell/
Publications

PubMed=30894629; DOI=10.1038/s41598-019-41277-z; PMCID=PMC6427001
Brett William Stringer, Bryan W. Day, Rochelle C.J. D'Souza, Paul R. Jamieson, Kathleen S. Ensbey, Zara C. Bruce, Yi-Chieh Lim, Kate Goasdoue, Carolin Offenhauser, Seckin Akgul, Suzanne Allan ...Show all 22 authors... , Thomas Robertson, Peter Geoffrey Lucas, Gert Tollesson, Scott Campbell, Craig Winter, Hong-Do Do, Alexander Dobrovic, Po-Ling Inglis, Rosalind L. Jeffree, Terrance Grant Johns, Andrew Wallace Boyd; Show fewer authors
A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 9:4902.1-4902.14(2019)

PubMed=31965010; DOI=10.1038/s41598-020-57850-w; PMCID=PMC6972897
Brett William Stringer, Bryan W. Day, Rochelle C.J. D'Souza, Paul R. Jamieson, Kathleen S. Ensbey, Zara C. Bruce, Yi-Chieh Lim, Kate Goasdoue, Carolin Offenhauser, Seckin Akgul, Suzanne Allan ...Show all 22 authors... , Thomas Robertson, Peter Geoffrey Lucas, Gert Tollesson, Scott Campbell, Craig Winter, Hong-Do Do, Alexander Dobrovic, Po-Ling Inglis, Rosalind L. Jeffree, Terrance Grant Johns, Andrew Wallace Boyd; Show fewer authors
Publisher correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.
Sci. Rep. 10:1185.1-1185.14(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VS45
Encyclopedic resources Wikidata; Q98128762
Gene expression databases GEO; GSM3347671
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number11