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Cellosaurus ICCSICi008-A (CVCL_VR76)

[Text version]
Cell line name ICCSICi008-A
Synonyms IC-AD1-F-iPS-4F-1; IC8-APOE 4/4
Accession CVCL_VR76
Resource Identification Initiative To cite this cell line use: ICCSICi008-A (RRID:CVCL_VR76)
Comments Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
From: Instituto Cajal; Madrid; Spain.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=31401456).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 74Y
Category Induced pluripotent stem cell
STR profile Source(s): BNLC

Markers:
AmelogeninX,Y
CSF1PO10,12
D5S81811,12
D7S8208,11
D13S3179,11
D16S53912,13
D21S1130
TH016
TPOX9,11
vWA17,18

Run an STR similarity search on this cell line
Web pages Provider; BNLC; -; https://www.isciii.es/documents/20119/880364/Caracteristicas+-+Documento+de+Depo%CC%81sito+IC-AD1-F-iPS-4F-1.pdf
Provider; BNLC; -; https://www.isciii.es/documents/20119/880377/Anexos%2520IC-AD1-F-iPS-4F-1.pdf
Publications

PubMed=31401456; DOI=10.1016/j.scr.2019.101522
Eva Diaz-Guerra, Elena P. Moreno-Jimenez, Itziar de Rojas, Cesar Rodriguez, Eva Rodriguez-Traver, Esther Arribas-Gonzalez, Maria Orera, Isabel Hernandez, Agustin Ruiz, Carlos Vicario-Abejon;
A collection of four integration-free iPSC lines derived from diagnosed sporadic Alzheimer's disease patients with different APOE alleles.
Stem Cell Res. 39:101522-101522(2019)

Cross-references
Cell line databases/resources hPSCreg; ICCSICi008-A
Encyclopedic resources Wikidata; Q94313355
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number12