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Cellosaurus TS/A-pc (CVCL_VQ63)

[Text version]
Cell line name TS/A-pc
Synonyms TSA-pc; TS/A p.c.; TS/A-parental cells
Accession CVCL_VQ63
Resource Identification Initiative To cite this cell line use: TS/A-pc (RRID:CVCL_VQ63)
Comments Caution: Termed "pc" for "parental cells" not because it is supposed to be identical to TS/A but because it is the parent cell line for a number of transfectants.
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Sequence variations
  • Mutation; MGI; MGI:98834; Trp53; Simple; p.Arg270His (c.809G>A); Zygosity=Unspecified (from parent cell line).
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/cAnNCrlBR.
Hierarchy Parent: CVCL_F736 (TS/A)
Sex of cell Female
Age at sampling 1Y8M
Category Cancer cell line
Publications

PubMed=7954438
Alessandra Allione, Manuela Consalvo, Patrizia Nanni, Pier-Luigi Lollini, Federica Cavallo, Mirella Giovarelli, Marco Forni, Alberto Gulino, Mario P. Colombo, Paolo Dellabona, Hanno Hock ...Show all 18 authors... , Thomas Blankenstein, Felicia M. Rosenthal, Bernd Gansbacher, Maria Carla Bosco, Tiziana Musso, Luca Gusella, Guido Forni; Show fewer authors
Immunizing and curative potential of replicating and nonreplicating murine mammary adenocarcinoma cells engineered with interleukin (IL)-2, IL-4, IL-6, IL-7, IL-10, tumor necrosis factor alpha, granulocyte-macrophage colony-stimulating factor, and gamma-interferon gene or admixed with conventional adjuvants.
Cancer Res. 54:6022-6026(1994)

PubMed=7989764; DOI=10.4049/jimmunol.153.12.5659
Federica Pericle, Mirella Giovarelli, Mario P. Colombo, Giuliana Ferrari, Piero Musiani, Andrea Modesti, Federica Cavallo, Francesco Di Pierro, Francesco Novelli, Guido Forni;
An efficient Th2-type memory follows CD8+ lymphocyte-driven and eosinophil-mediated rejection of a spontaneous mouse mammary adenocarcinoma engineered to release IL-4.
J. Immunol. 153:5659-5673(1994)

PubMed=31783695; DOI=10.3390/cancers11121889; PMCID=PMC6966465
Carla De Giovanni, Giordano Nicoletti, Lorena Landuzzi, Arianna Palladini, Pier-Luigi Lollini, Patrizia Nanni;
Bioprofiling TS/A murine mammary cancer for a functional precision experimental model.
Cancers (Basel) 11:1889.1-1889.20(2019)

Cross-references
Encyclopedic resources Wikidata; Q98133613
Entry history
Entry creation13-Nov-2018
Last entry update29-Jun-2023
Version number6