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Cellosaurus Mela15 (CVCL_VN58)

[Text version]
Cell line name Mela15
Synonyms MELA15
Accession CVCL_VN58
Resource Identification Initiative To cite this cell line use: Mela15 (RRID:CVCL_VN58)
Comments Doubling time: 30 hours (Direct_author_submission).
Miscellaneous: Cell line information from personal communication of Marlow, Laura A.
Derived from site: Metastatic; Inguinal lymph node; UBERON=UBERON_0001542.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (Direct_author_submission).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO10,11
D3S135815,18
D5S81811,12
D7S82011
D8S117913,14
D13S3178,11
D16S53910
D18S5115
FGA20
TH016,9
TPOX8
vWA17,19

Run an STR similarity search on this cell line
Publications

DOI=10.1158/1538-7445.AM2015-2417
Harris A.L., Marlow L.A., Mathias A.C., Dawson L.K., Durham W.F., Meshaw K.A., Mullin R.J., Small D.L., Synnott A., Wu K., Milosevic D., Netzel B.C., Grebe S.K.G., Markovic S.N., Copland J.A. 3rd
Characterization of novel patient derived melanoma xenografts and cell lines in response to targeted therapies.
Cancer Res. 75 Suppl. 15:2417-2417(2015)

PubMed=29416592; DOI=10.18632/oncotarget.21545; PMCID=PMC5787466
von Roemeling C.A., Caulfield T.R., Marlow L.A., Bok I., Wen J., Miller J.L., Hughes R., Hazlehurst L.A., Pinkerton A.B., Radisky D.C., Tun H.W., Kim Y.S.B., Lane A.L., Copland J.A. 3rd
Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy.
Oncotarget 9:3-20(2018)

Cross-references
Cell line collections (Providers) ABM; T8319
Cell line databases/resources cancercelllines; CVCL_VN58
Encyclopedic resources Wikidata; Q95988714
Entry history
Entry creation07-Sep-2018
Last entry update10-Apr-2025
Version number10