| Cell line name |
LMWT5 |
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| Accession |
CVCL_VN52 |
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| Resource Identification Initiative |
To cite this cell line use: LMWT5 (RRID:CVCL_VN52) |
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| Comments |
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084. |
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| Sequence variations |
- Mutation; HGNC; HGNC:9065; PLCG1; Simple; p.Ser520Phe (c.1559C>T); Zygosity=Heterozygous (CelloPub=CLPUB00592).
- Mutation; HGNC; HGNC:9065; PLCG1; Simple; p.Arg748His (c.2243G>A); Zygosity=Heterozygous (CelloPub=CLPUB00592).
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| Disease |
Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Category |
Cancer cell line |
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| Publications | PubMed=27193821; DOI=10.1111/cas.12971; PMCID=PMC4982578
Hiroo Hasegawa, Reid P. Bissonnette, Mireille Gillings, Daisuke Sasaki, Hiroaki Taniguchi, Hideaki Kitanosono, Kazuto Tsuruda, Kousuke Kosai, Naoki Uno, Yoshitomo Morinaga, Yoshitaka Imaizumi ...Show all 13 authors... , Yasushi Miyazaki, Katsunori Yanagihara; Show fewer authors
Induction of apoptosis by HBI-8000 in adult T-cell leukemia/lymphoma is associated with activation of Bim and NLRP3.
Cancer Sci. 107:1124-1133(2016) CLPUB00592
Varsha Maheshkumar Patel;
Functional interrogations of phospholipase c gamma 1 (PLCG1) mutations in Sezary syndrome.
Thesis PhD (2019); King's College London; London; United Kingdom |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q95982649
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| Entry history |
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| Entry creation | 07-Sep-2018 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 10 |
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