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Cellosaurus ORL11 (CVCL_VN28)

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Cell line name ORL11
Synonyms ORL-11
Accession CVCL_VN28
Resource Identification Initiative To cite this cell line use: ORL11 (RRID:CVCL_VN28)
Comments Population: Japanese.
Characteristics: Supports HCV replication.
Characteristics: Transfected with ORN/C-5B/QR,KE,SR RNA, a construct containing Renilla reniformis renilla-type luciferase, neo and genome-length HCV RNA from O strain (genotype 1b).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P27652; Renilla reniformis renilla-type luciferase.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VN26 (Li-23)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=19720094; DOI=10.1016/j.virusres.2009.08.006
Nobuyuki Kato, Kyoko Mori, Ken-ichi Abe, Hiromichi Dansako, Misao Kuroki, Yasuo Ariumi, Takaji Wakita, Masanori Ikeda;
Efficient replication systems for hepatitis C virus using a new human hepatoma cell line.
Virus Res. 146:41-50(2009)

PubMed=21320556; DOI=10.1016/j.virusres.2011.02.005
Kyoko Mori, Masanori Ikeda, Yasuo Ariumi, Hiromichi Dansako, Takaji Wakita, Nobuyuki Kato;
Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system.
Virus Res. 157:61-70(2011)

Cross-references
Encyclopedic resources Wikidata; Q98128370
Entry history
Entry creation07-Sep-2018
Last entry update14-Aug-2025
Version number8