Cellosaurus HeLa/Fucci(CA)2 (CVCL_VM98)
Cell line name | HeLa/Fucci(CA)2 |
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Synonyms | HeLa/Fucci(CA)2 #3 |
Accession | CVCL_VM98 |
Resource Identification Initiative | To cite this cell line use: HeLa/Fucci(CA)2 (RRID:CVCL_VM98) |
Comments | Population: African American. Characteristics: Used for study of cell cycle progression thanks to the inclusion of a Fucci(CA2) (Fluorescent Ubiquitination-based Cell Cycle Indicator) construct. Characteristics: Transfected with the Fucci(CA)2 probe which consist of the fusion of mCherry to the ubiquitination domain of human CDT1 (aa 1-100) but with the Cy motif 68-RRL-70 replaced by AAA and of monomeric Venus (mVenus) to the ubiquitination domain of human geminin (aa 1-110). Transfected with: HGNC; 24576; CDT1 (with p.Ser101_Leu546del and p.Arg68Ala, p.Arg69Ala and p.Leu70Ala). Transfected with: HGNC; 17493; GMNN (with p.Tyr111_Ile209del). Transfected with: UniProtKB; X5DSL3; Anaplasma marginale mCherry fluorescent protein. Transfected with: Venus, a bright yellow fluorescent protein derived from YFP. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0058 (HeLa S3) |
Sex of cell | Female |
Age at sampling | 30Y6M |
Category | Cancer cell line |
Publications | PubMed=29107535; DOI=10.1016/j.molcel.2017.10.001 |
Cross-references | |
Cell line collections (Providers) | RCB; RCB4676 |
Encyclopedic resources | Wikidata; Q94101207 |
Entry history | |
Entry creation | 07-Sep-2018 |
Last entry update | 29-Jun-2023 |
Version number | 8 |