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Cellosaurus WTC11 HOPX-NLS-eGFP (CVCL_VM46)

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Cell line name WTC11 HOPX-NLS-eGFP
Accession CVCL_VM46
Resource Identification Initiative To cite this cell line use: WTC11 HOPX-NLS-eGFP (RRID:CVCL_VM46)
Comments Population: Japanese.
Characteristics: Using TALEN, a conditionally expressed HOPX-NLS-eGFP construct was introduced in the AAVS1 safe harbor locus (PubMed=30290179).
Genetic integration: Method=TALEN; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=TALEN; Gene=HGNC; HGNC:24961; HOPX.
Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_Y803 (GM25256)
Sex of cell Male
Age at sampling 30Y
Category Induced pluripotent stem cell
Publications

PubMed=30290179; DOI=10.1016/j.stem.2018.09.009; PMCID=PMC6220122
Clayton E. Friedman, Quan Nguyen, Samuel W. Lukowski, Abbigail Helfer, Han Sheng Chiu, Jason Miklas, Shiri Levy, Sheng-Bao Suo, Jing-Dong Jackie Han, Pierre Osteil, Guang-Dun Peng ...Show all 26 authors... , Nai-He Jing, Gregory J. Baillie, Anne Senabouth, Angelika N. Christ, Timothy James Caird Bruxner, Charles E. Murry, Emily S. Wong, Jun Ding, Yu-Liang Wang, James Hudson, Hannele Ruohola-Baker, Ziv Bar-Joseph, Patrick Ping Leu Tam, Joseph E. Powell, Nathan J. Palpant; Show fewer authors
Single-cell transcriptomic analysis of cardiac differentiation from human PSCs reveals HOPX-dependent cardiomyocyte maturation.
Cell Stem Cell 23:586-598.e8(2018)

Cross-references
Encyclopedic resources Wikidata; Q98135094
Entry history
Entry creation07-Sep-2018
Last entry update10-Apr-2025
Version number10