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Cellosaurus UM-MCC565 (CVCL_VM06)

[Text version]
Cell line name UM-MCC565
Synonyms MCC565
Accession CVCL_VM06
Resource Identification Initiative To cite this cell line use: UM-MCC565 (RRID:CVCL_VM06)
Comments Characteristics: Established from a mouse tumor xenograft in NOD/SCID/IL2RgammaNULL mice.
Doubling time: 36 hours (PubMed=24614157).
Transformant: NCBI_TaxID; 493803; Merkel cell polyomavirus (MCPyV).
Disease Merkel cell carcinoma (NCIt: C9231)
Cutaneous neuroendocrine carcinoma (ORDO: Orphanet_79140)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 71Y
Category Cancer cell line
Publications

PubMed=23223137; DOI=10.1038/jid.2012.445; PMCID=PMC3597750
Harms P.W., Patel R.M., Verhaegen M.E., Giordano T.J., Nash K.T., Johnson C.N., Daignault-Newton S., Thomas D.G., Gudjonsson J.E., Elder J.T., Dlugosz A.A., Johnson T.M., Fullen D.R., Bichakjian C.K.
Distinct gene expression profiles of viral- and nonviral-associated Merkel cell carcinoma revealed by transcriptome analysis.
J. Invest. Dermatol. 133:936-945(2013)

PubMed=24614157; DOI=10.1038/jid.2014.138; PMCID=PMC4181590
Verhaegen M.E., Mangelberger D., Weick J.W., Vozheiko T.D., Harms P.W., Nash K.T., Quintana E., Baciu P., Johnson T.M., Bichakjian C.K., Dlugosz A.A.
Merkel cell carcinoma dependence on bcl-2 family members for survival.
J. Invest. Dermatol. 134:2241-2250(2014)

Cross-references
Encyclopedic resources Wikidata; Q98134072
Gene expression databases GEO; GSM973035
Entry history
Entry creation07-Sep-2018
Last entry update21-Mar-2023
Version number5