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Cellosaurus MB49-I (CVCL_VL62)

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Cell line name MB49-I
Accession CVCL_VL62
Resource Identification Initiative To cite this cell line use: MB49-I (RRID:CVCL_VL62)
Comments Characteristics: Has an invasive and metastatic phenotype.
Characteristics: Established after 13 consecutive passages of MB49 through subcutaneous injection in the left flank of C57BL/6J male mice.
Karyotypic information: Has lost chromosome Y (PubMed=22559978).
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Disease Mouse bladder transitional cell carcinoma (NCIt: C25823)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/ICRF-a(t).
Hierarchy Parent: CVCL_7076 (MB49)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=19539312; DOI=10.1016/j.juro.2009.03.076
Catalina Lodillinsky, Vanina Rodriguez, Liliana Vauthay, Eduardo Sandes, Alberto Casabe, Ana Maria Eijan;
Novel invasive orthotopic bladder cancer model with high cathepsin B activity resembling human bladder cancer.
J. Urol. 182:749-755(2009)

PubMed=22559978; DOI=10.1016/j.cancergen.2012.02.002
Victoria T. Fabris, Catalina Lodillinsky, Maria Betina Pampena, Denise Belgorosky, Claudia Lanari, Ana Maria Eijan;
Cytogenetic characterization of the murine bladder cancer model MB49 and the derived invasive line MB49-I.
Cancer Genet. 205:168-176(2012)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus Christiaan de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

PubMed=30867744; DOI=10.3892/ol.2019.9995; PMCID=PMC6396118
Marina Alberto, Hector Adrian Cuello, Cynthia Anabella Gulino, Marina Pifano, Denise Belgorosky, Mariano Rolando Gabri, Ana Maria Eijan, Valeria Ines Segatori;
Expression of bladder cancer-associated glycans in murine tumor cell lines.
Oncol. Lett. 17:3141-3150(2019)

Cross-references
Encyclopedic resources Wikidata; Q95985487
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number8