Cellosaurus cell line UKRV-Mel-32 (CVCL

Cellosaurus UKRV-Mel-32 (CVCL_VK54)

Cross-references
Cell line name	UKRV-Mel-32
Synonyms	UKRVMEL32
Accession	CVCL_VK54
Resource Identification Initiative	To cite this cell line use: UKRV-Mel-32 (RRID:CVCL_VK54)
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=26909863). Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (PubMed=26909863). Gene fusion; HGNC; HGNC:7413; MTAP + HGNC; HGNC:34341; CDKN2B-AS1; Name(s)=MTAP-ANRIL (PubMed=26909863). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Sex unspecified
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=23348503; DOI=10.1126/science.1230062 Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar; TERT promoter mutations in familial and sporadic melanoma. Science 339:959-961(2013) PubMed=26909863; DOI=10.18632/oncotarget.7503; PMCID=PMC4941330 Hua-Ping Xie, P. Sivaramakrishna Rachakonda, Barbara Heidenreich, Eduardo Nagore, Antje Sucker, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar; Mapping of deletion breakpoints at the CDKN2A locus in melanoma: detection of MTAP-ANRIL fusion transcripts. Oncotarget 7:16490-16504(2016)
Encyclopedic resources	Wikidata; Q98133996
Polymorphism and mutation databases	Cosmic; 2686538
Entry history
Entry creation	07-Sep-2018
Last entry update	19-Dec-2024
Version number	6