Cellosaurus cell line Co53 (CVCL

Cross-references
Cell line name	Co53
Accession	CVCL_VK05
Resource Identification Initiative	To cite this cell line use: Co53 (RRID:CVCL_VK05)
Sequence variations	Mutation; HGNC; HGNC:173; ACVR2A; Simple; p.Lys437Argfs5 (c.1310delA); dbSNP=rs764719749; Zygosity=Homozygous (PubMed=12615714). Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Lys128Serfs35 (c.383delA); ClinVar=VCV000477546; Zygosity=Heterozygous (PubMed=12615714). Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Leu452Pro (c.1355T>C); ClinVar=VCV000930524; Zygosity=Heterozygous (PubMed=12615714).
Disease	Colon carcinoma (NCIt: C4910)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=12615714 Paula M. Hempen, Lin Zhang, Ravi K. Bansal, Christine A. Iacobuzio-Donahue, Kathleen M. Murphy, Anirban Maitra, Bert Vogelstein, Robert H. Whitehead, Sanford David Markowitz, James K.V. Willson, Charles J. Yeo ...Show all 13 authors... , Ralph H. Hruban, Scott E. Kern; Show fewer authors Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers. Cancer Res. 63:994-999(2003)
Cell line databases/resources	cancercelllines; CVCL_VK05
Encyclopedic resources	Wikidata; Q93456392
Polymorphism and mutation databases	Cosmic; 2667977
Entry history
Entry creation	07-Sep-2018
Last entry update	19-Dec-2024
Version number	8