Cellosaurus cell line UTE4 (CVCL

Cellosaurus UTE4 (CVCL_VK04)

Cross-references
Cell line name	UTE4
Accession	CVCL_VK04
Resource Identification Initiative	To cite this cell line use: UTE4 (RRID:CVCL_VK04)
Comments	Microsatellite instability: Stable (MSS) (PubMed=27894751).
Sequence variations	Mutation; HGNC; HGNC:9177; POLE; Simple; p.Ala957Val; Zygosity=Unspecified (PubMed=27894751).
Disease	Ovarian endometrioid adenocarcinoma (NCIt: C7979) Endometrioid carcinoma of ovary (ORDO: Orphanet_454723)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	65Y
Category	Cancer cell line
Publications	PubMed=27894751; DOI=10.1016/j.ygyno.2016.11.023; PMCID=PMC5183545 Stefania Bellone, Eliana Bignotti, Silvia Lonardi, Francesca Ferrari, Floriana Centritto, Alice Masserdotti, Francesca Pettinella, Jonathan D. Black, Gulden Menderes, Gary Altwerger, Pei Hui ...Show all 29 authors... , Salvatore Lopez, Christopher de Haydu, Elena Bonazzoli, Federica Predolini, Luca Zammataro, Emiliano Cocco, Federico Ferrari, Antonella Ravaggi, Chiara Romani, Fabio Facchetti, Enrico Sartori, Franco Edoardo Odicino, Dan-Arin Silasi, Babak Litkouhi, Elena Ratner, Masoud Azodi, Peter E. Schwartz, Alessandro D. Santin; Show fewer authors Polymerase epsilon (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro. Gynecol. Oncol. 144:146-152(2017)
Encyclopedic resources	Wikidata; Q98134401
Polymorphism and mutation databases	Cosmic; 2640555
Entry history
Entry creation	07-Sep-2018
Last entry update	19-Dec-2024
Version number	6