| Cell line name |
SCCIC21 |
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| Accession |
CVCL_VJ54 |
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| Resource Identification Initiative |
To cite this cell line use: SCCIC21 (RRID:CVCL_VJ54) |
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| Sequence variations |
- Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Val1867Ile (c.5599G>A); Zygosity=Unspecified (PubMed=24662767).
- Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Gln2405Pro (c.7214A>C); Zygosity=Unspecified (PubMed=24662767).
|
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| Disease |
Skin squamous cell carcinoma (NCIt: C4819) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Category |
Cancer cell line |
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| Publications | PubMed=24662767; DOI=10.1038/jid.2014.154; PMCID=PMC4753672
Andrew P. South, Karin J. Purdie, Stephen A. Watt, Sam Haldenby, Nicoline Y. den Breems, Michelle Dimon, Sarah T. Arron, Michael J. Kluk, Jon Christopher Aster, Angela McHugh, Dylan J. Xue ...Show all 17 authors... , Jasbani H.S. Dayal, Kim S. Robinson, S.M. Hasan Rizvi, Charlotte Mary Proby, Catherine A. Harwood, Irene May Leigh; Show fewer authors
NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis.
J. Invest. Dermatol. 134:2630-2638(2014) |
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| Cross-references |
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| Encyclopedic resources |
Wikidata; Q98129379
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| Polymorphism and mutation databases |
Cosmic; 2688667
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| Entry history |
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| Entry creation | 07-Sep-2018 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 6 |
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