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Cellosaurus HEK-TLR4-YFP/MD-2 (CVCL_VI45)

[Text version]
Cell line name HEK-TLR4-YFP/MD-2
Synonyms HEK-TLR4YFP/MD-2
Accession CVCL_VI45
Resource Identification Initiative To cite this cell line use: HEK-TLR4-YFP/MD-2 (RRID:CVCL_VI45)
Comments Characteristics: Transfected with YFP fused in frame to the C-terminus of TLR4.
Transfected with: HGNC; 17156; LY96.
Transfected with: HGNC; 11850; TLR4.
Transfected with: UniProtKB; P42212; YFP (modified GFP at G-65, L-68, A-72, Y-203 and L-231).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VI44 (HEK-TLR4-YFP)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=12324469; DOI=10.1074/jbc.M207873200
Latz E., Visintin A., Lien E., Fitzgerald K.A., Monks B.G., Kurt-Jones E.A., Golenbock D.T., Espevik T.
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the Toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction.
J. Biol. Chem. 277:47834-47843(2002)

Cross-references
Cell line collections (Providers) BEI_Resources; NR-9315
Encyclopedic resources Wikidata; Q54882327
Entry history
Entry creation14-May-2018
Last entry update29-Jun-2023
Version number5