• Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Thr541Ala (c.1621A>G); ClinVar=VCV000134640; Zygosity=Homozygous; Note=Probable SNP (PubMed=29330294).
  

PubMed=29330294; DOI=10.1158/1541-7786.MCR-17-0163
Daniel Benten, Yasmin Behrang, Ludmilla Unrau, Victoria Weissmann, Gerrit Wolters-Eisfeld, Susanne Burdak-Rothkamm, Felix R. Stahl, Martin Anlauf, Patricia Grabowski, Markus Mobs, Jan Dieckhoff ...Show all 19 authors... , Bence Sipos, Martina Fahl, Corinna Eggers, Daniel Perez, Maximilian Bockhorn, Jakob Robert Izbicki, Ansgar W. Lohse, Jorg Schrader; Show fewer authors
Establishment of the first well-differentiated human pancreatic neuroendocrine tumor model.
Mol. Cancer Res. 16:496-507(2018)

CLPUB00598
Yasmin Behrang;
Establishment and characterization of a new human, highly differentiated and functionally active tumor model of a pancreatic neuroendocrine tumor.
Thesis MD (2020); University of Hamburg; Hamburg; Germany

PubMed=36269546; DOI=10.1007/s13402-022-00727-z; PMCID=PMC9747820
Fabrice Viol, Bence Sipos, Martina Fahl, Till Sebastian Clauditz, Tania Amin, Malte Kriegs, Maike Nieser, Jakob Robert Izbicki, Samuel Huber, Ansgar W. Lohse, Jorg Schrader;
Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy.
Cell. Oncol. (Dordr.) 45:1401-1419(2022)