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Cellosaurus PAM-pCD163 (CVCL_VG78)

[Text version]
Cell line name PAM-pCD163
Synonyms IPAM-CD163
Accession CVCL_VG78
Resource Identification Initiative To cite this cell line use: PAM-pCD163 (RRID:CVCL_VG78)
Comments Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome virus type 1 and type 2 (PRRSV-1/2).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
Genetic integration: Method=Transfection; Gene=VGNC; VGNC:112737; Pig CD163.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299.
Cell type: Alveolar macrophage; CL=CL_0000583.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Landrace; VBO=VBO_0001161.
Hierarchy Parent: CVCL_0F14 (IPAM 3D4/21)
Sex of cell Sex unspecified
Age at sampling 12W
Category Transformed cell line
Publications

PubMed=19900480; DOI=10.1016/j.jviromet.2009.11.003
Yoo Jin Lee, Choi-Kyu Park, Eeuri Nam, Seong-Hee Kim, O-Soo Lee, Du Sik Lee, Changhee Lee;
Generation of a porcine alveolar macrophage cell line for the growth of porcine reproductive and respiratory syndrome virus.
J. Virol. Methods 163:410-415(2010)

PubMed=28871180; DOI=10.1038/s41598-017-09948-x; PMCID=PMC5583235
Elena Garcia Sanchez, Elena Riera, Marisa Nogal, Carmina Gallardo, Paloma Fernandez, Raquel Bello-Morales, Jose Antonio Lopez-Guerrero, Carol Geralyn Chitko-McKown, Jurgen A. Richt, Yolanda Revilla;
Phenotyping and susceptibility of established porcine cells lines to African swine fever virus infection and viral production.
Sci. Rep. 7:10369.1-10369.13(2017)

Cross-references
Encyclopedic resources Wikidata; Q54937493
Entry history
Entry creation14-May-2018
Last entry update14-Aug-2025
Version number13