Cellosaurus cell line 149RCa (CVCL

Cellosaurus 149RCa (CVCL_VF96)

[Text version]

Cell line name

149RCa

Accession

CVCL_VF96

Resource Identification Initiative

To cite this cell line use: 149RCa (RRID:CVCL_VF96)

Comments

Population: Chinese.
Doubling time: 26.75 hours (PubMed=29880898).
Omics: Genomics; Whole genome sequencing.
Derived from site: Metastatic; Penis; UBERON=UBERON_0000989.

Sequence variations

Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Ser25Ter (c.74C>G); Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly13Val (c.38G>T); ClinVar=VCV000180848; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro72Arg (c.215C>G); ClinVar=VCV000012351; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Unspecified (PubMed=29880898).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Unspecified (PubMed=29880898).

Disease

Squamous cell carcinoma of the penis (NCIt: C7729)
Squamous cell carcinoma of the penis (ORDO: Orphanet_398058)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_VL37 ! 149RM

Sex of cell

Male

Age at sampling

33Y

Category

Cancer cell line

STR profile

Source(s): PubMed=28344882; PubMed=29880898

Markers:

Amelogenin	X,Y
CSF1PO	10,11
D5S818	10
D7S820	12
D13S317	9,12
D16S539	12
TH01	6,9
TPOX	8
vWA	14,16

Publications

PubMed=28344882; DOI=10.1080/2162402X.2016.1269047; PMCID=PMC5353932
Chuang-Zhong Deng, Zai-Shang Li, Sheng-Jie Guo, Peng Chen, Xiao-Feng Chen, Qiang-Hua Zhou, Jie-Ping Chen, Xing-Su Yu, Xiao-Liang Wu, Wen-Juan Ma, Qian-Kun Xie ...Show all 20 authors... , Yun-Lin Ye, Yong-Hong Li, Zi-Ke Qin, Zhuo-Wei Liu, Ran-Yi Liu, Zhen-Feng Zhang, Kai Yao, Hui Han, Fang-Jian Zhou; Show fewer authors
Tumor PD-L1 expression is correlated with increased TILs and poor prognosis in penile squamous cell carcinoma.
OncoImmunology 6:e1269047.1-e1269047.8(2017)

PubMed=29880898; DOI=10.1038/s41419-018-0736-1; PMCID=PMC5992159
Qiang-Hua Zhou, Chuang-Zhong Deng, Zai-Shang Li, Jie-Ping Chen, Kai Yao, Kang-Bo Huang, Tian-Yu Liu, Zhuo-Wei Liu, Zi-Ke Qin, Fang-Jian Zhou, Wei Huang ...Show all 13 authors... , Hui Han, Ran-Yi Liu; Show fewer authors
Molecular characterization and integrative genomic analysis of a panel of newly established penile cancer cell lines.
Cell Death Dis. 9:684.1-684.14(2018)

Cross-references

Cell line collections (Providers)

ABM; T8331

Cell line databases/resources

cancercelllines; CVCL_VF96

Encyclopedic resources

Wikidata; Q54581943

Polymorphism and mutation databases

Cosmic; 2806956

Entry history

Entry creation

14-May-2018

Last entry update

10-Apr-2025

Version number