Cellosaurus cell line FUS2 corrected (CVCL

Cellosaurus FUS2 corrected (CVCL_VF87)

Cross-references
Cell line name	FUS2 corrected
Synonyms	ISOGENIC CNTL; R495QfsX527c.1483insC
Accession	CVCL_VF87
Resource Identification Initiative	To cite this cell line use: FUS2 corrected (RRID:CVCL_VF87)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:4010; FUS; Simple_corrected; p.Arg495Glufs*34 (c.1483delC); Zygosity=Heterozygous; Note=By CRISPR/Cas9 (PubMed=28082870).
Disease	Amyotrophic lateral sclerosis 6, with or without frontotemporal dementia (NCIt: C168750) Frontotemporal dementia with motor neuron disease (ORDO: Orphanet_275872)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_VF86 (FUS2)
Sex of cell	Male
Age at sampling	28Y
Category	Induced pluripotent stem cell
Publications	PubMed=28082870; DOI=10.3389/fncel.2016.00290; PMCID=PMC5183648 Julia Higelin, Maria Demestre, Stefan Putz, Jan P. Delling, Christian Jacob, Anne-Kathrin Lutz, Julia Bausinger, Anne-Kathrin Huber, Moritz Klingenstein, Gotthold Barbi, Gunter Speit ...Show all 17 authors... , Annemarie Huebers, Jochen H. Weishaupt, Andreas Hermann, Stefan Liebau, Albert Christian Ludolph, Tobias M. Boeckers; Show fewer authors FUS mislocalization and vulnerability to DNA damage in ALS patients derived hiPSCs and aging motoneurons. Front. Cell. Neurosci. 10:290.1-290.21(2016)
Cell line databases/resources	SKIP; SKIP001734
Encyclopedic resources	Wikidata; Q54835273
Entry history
Entry creation	14-May-2018
Last entry update	10-Apr-2025
Version number	13