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Cellosaurus UCLi009-A (CVCL_VF13)

[Text version]
Cell line name UCLi009-A
Synonyms R155C 1; CB1D; MUT 1
Accession CVCL_VF13
Resource Identification Initiative To cite this cell line use: UCLi009-A (RRID:CVCL_VF13)
Comments From: University College London; London; United Kingdom.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Frontotemporal dementia (NCIt: C84719)
Behavioral variant of frontotemporal dementia (ORDO: Orphanet_275864)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VF14 ! UCLi009-B
Sex of cell Female
Age at sampling 43Y
Category Induced pluripotent stem cell
Publications

PubMed=28360103; DOI=10.1074/jbc.M116.762898
Ludtmann M.H.R., Arber C., Bartolome F., de Vicente M., Preza E., Carro E., Houlden H., Gandhi S., Wray S., Abramov A.Y.
Mutations in valosin-containing protein (VCP) decrease ADP/ATP translocation across the mitochondrial membrane and impair energy metabolism in human neurons.
J. Biol. Chem. 292:8907-8917(2017)

PubMed=28564594; DOI=10.1016/j.celrep.2017.05.024
Hall C.E., Yao Z., Choi M., Tyzack G.E., Serio A., Luisier R., Harley J., Preza E., Arber C., Crisp S.J., Watson P.M.D., Kullmann D.M., Abramov A.Y., Wray S., Burley R., Loh S.H.Y., Martins L.M., Stevens M.M., Luscombe N.M., Sibley C.R., Lakatos A., Ule J., Gandhi S., Patani R.
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS.
Cell Rep. 19:1739-1749(2017)

Cross-references
Cell line databases/resources hPSCreg; UCLi009-A
Biological sample resources BioSamples; SAMEA4675625
Encyclopedic resources Wikidata; Q54989678
Entry history
Entry creation14-May-2018
Last entry update29-Jun-2023
Version number11