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Cellosaurus US/VOT-N33 (CVCL_VC37)

[Text version]
Cell line name US/VOT-N33
Synonyms VOT-N33; University of Sheffield/Ventral OTocyst-Neuroblast 33
Accession CVCL_VC37
Resource Identification Initiative To cite this cell line use: US/VOT-N33 (RRID:CVCL_VC37)
Comments Characteristics: Neuroblast cell line suitable for studies on: inner ear development; gene expression and function of inner ear-specific genes; in vitro screening for gene activation and promoter analysis; ototoxicity; and in vitro analysis of inherited deafness mutations and of ion channels, receptors and signalling pathways in vitro.
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic ear, inner ear, otocyst; UBERON=UBERON_0003051.
Cell type: Neuroblast; CL=CL_0000031.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (CBA/Ca x C57BL/10)Tg(H2Kb-tsA58) Immortomouse.
Sex of cell Sex unspecified
Age at sampling 10-11FD
Category Conditionally immortalized cell line
Publications

PubMed=15499550; DOI=10.1002/dvdy.20187
Grace Lawoko-Kerali, Marta Milo, Dawn Davies, Antony Halsall, Richard J. Helyer, Claire M. Johnson, Marcelo N. Rivolta, Michael A. Tones, Matthew C. Holley;
Ventral otic cell lines as developmental models of auditory epithelial and neural precursors.
Dev. Dyn. 231:801-814(2004)

Cross-references
Cell line collections (Providers) CancerTools; 153626
Ximbio; 153626
Encyclopedic resources Wikidata; Q54991849
Entry history
Entry creation14-May-2018
Last entry update14-Aug-2025
Version number12