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Cellosaurus SHSY5Y-B7H6 (CVCL_VA24)

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Cell line name SHSY5Y-B7H6
Accession CVCL_VA24
Resource Identification Initiative To cite this cell line use: SHSY5Y-B7H6 (RRID:CVCL_VA24)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:42400; NCR3LG1.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0019 (SH-SY5Y)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=29453518; DOI=10.1007/s00262-018-2124-1; PMCID=PMC11028385
Albert T. Gacerez, Casey K. Hua, Margaret E. Ackerman, Charles L. Sentman;
Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression.
Cancer Immunol. Immunother. 67:749-759(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VA24
Encyclopedic resources Wikidata; Q54953398
Entry history
Entry creation14-May-2018
Last entry update19-Dec-2024
Version number11