Cellosaurus cell line RMA-B7H6 (CVCL

Cross-references
Cell line name	RMA-B7H6
Synonyms	RMA/B7H6
Accession	CVCL_VA23
Resource Identification Initiative	To cite this cell line use: RMA-B7H6 (RRID:CVCL_VA23)
Comments	Genetic integration: Method=Transduction; Gene=HGNC; HGNC:42400; NCR3LG1. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE). Transformant: NCBI_TaxID; 11938; Rauscher murine leukemia virus (R-MuLV). Derived from site: In situ; Ascites; UBERON=UBERON_0007795. Cell type: T-cell; CL=CL_0000084.
Disease	Mouse leukemia (NCIt: C21604)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6.
Hierarchy	Parent: CVCL_J385 (RMA)
Category	Cancer cell line
Publications	PubMed=25830550; DOI=10.1038/gt.2015.29; PMCID=PMC4529373 Ming-Ru Wu, Tong Zhang, Leslie R. DeMars, Charles L. Sentman; B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity. Gene Ther. 22:675-684(2015) PubMed=29453518; DOI=10.1007/s00262-018-2124-1; PMCID=PMC11028385 Albert T. Gacerez, Casey K. Hua, Margaret E. Ackerman, Charles L. Sentman; Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression. Cancer Immunol. Immunother. 67:749-759(2018)
Encyclopedic resources	Wikidata; Q54950644
Entry history
Entry creation	14-May-2018
Last entry update	14-Aug-2025
Version number	9