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Cellosaurus B16F10-B7H6 (CVCL_VA21)

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Cell line name B16F10-B7H6
Synonyms B16F10/B7H6
Accession CVCL_VA21
Resource Identification Initiative To cite this cell line use: B16F10-B7H6 (RRID:CVCL_VA21)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:42400; NCR3LG1.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_0159 (B16-F10)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=25830550; DOI=10.1038/gt.2015.29; PMCID=PMC4529373
Ming-Ru Wu, Tong Zhang, Leslie R. DeMars, Charles L. Sentman;
B7H6-specific chimeric antigen receptors lead to tumor elimination and host antitumor immunity.
Gene Ther. 22:675-684(2015)

PubMed=29453518; DOI=10.1007/s00262-018-2124-1; PMCID=PMC11028385
Albert T. Gacerez, Casey K. Hua, Margaret E. Ackerman, Charles L. Sentman;
Chimeric antigen receptors with human scFvs preferentially induce T cell anti-tumor activity against tumors with high B7H6 expression.
Cancer Immunol. Immunother. 67:749-759(2018)

Cross-references
Encyclopedic resources Wikidata; Q54752459
Entry history
Entry creation14-May-2018
Last entry update14-Aug-2025
Version number9