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Cellosaurus HCC2270 (CVCL_V635)

[Text version]
Cell line name HCC2270
Synonyms Hamon Cancer Center 2270
Accession CVCL_V635
Resource Identification Initiative To cite this cell line use: HCC2270 (RRID:CVCL_V635)
Comments Population: Caucasian.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Miscellaneous: Direct author submission of STR profile from Girard, Luc & Gazdar, Adi F.
HLA typing Source: PubMed=26589293
Class I
HLA-AA*01:01,03:01
HLA-BB*08:01,50:01
HLA-CC*06:02,07:01
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,14
D3S135815
D5S81811
D7S82010,12
D8S117910,12
D13S3178,11
D16S53913
D18S5114
D21S1129,30
FGA18,24
Penta D12,14
Penta E5,13
TH019
TPOX10,11
vWA17,18

Run an STR similarity search on this cell line
Web pages Provider; UT Southwestern; -; https://www.utsouthwestern.edu/edumedia/edufiles/about_us/admin_offices/technology_development/available_technologies/cell-lines.pdf
Publications

PubMed=25485619; DOI=10.1038/nbt.3080
Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878
Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle;
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=31803961; DOI=10.1002/jcb.29564; PMCID=PMC7496084
James L. Mulshine, Peter Ujhazy, Melissa Antman, Christine M. Burgess, Igor A. Kuzmin, Paul A. Bunn Jr., Bruce E. Johnson, Jack Alan Roth, Harvey I. Pass, Sheila M. Ross, Carolyn R. Aldige ...Show all 13 authors... , Ignacio Ivan Wistuba, John D. Minna; Show fewer authors
From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
J. Cell. Biochem. 121:3986-3999(2020)

Cross-references
Biological sample resources BioSample; SAMN03473069
Chemistry resources PharmacoDB; HCC2270_491_2019
Encyclopedic resources Wikidata; Q54881639
Experimental variables resources EFO; EFO_0006430
Gene expression databases ArrayExpress; E-MTAB-2706
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation16-Apr-2014
Last entry update14-Aug-2025
Version number16