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Cellosaurus SF172 (CVCL_V613)

[Text version]
Cell line name SF172
Synonyms SF-172
Accession CVCL_V613
Resource Identification Initiative To cite this cell line use: SF172 (RRID:CVCL_V613)
Comments Problematic cell line: Probably misidentified/contaminated. Except of a loss of an allele of TH01 the STR profile of SF172 is identical to that of SF763. Furthermore we could not find in the literature any trace of the exact origin of SF172 and, according to a personal communication of Shai A. from the UCSF Biorepository, there is no record of SF172 in their system while SF763 is registered there. The TP53 mutation recorded for SF763 is also identical to the one in SF172.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 24 hours (PubMed=25984343).
Omics: Deep exome analysis.
Omics: shRNA library screening.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg158Leu (c.473G>T); ClinVar=VCV000528248; Zygosity=Homozygous (DepMap).
Genome ancestry Source: PubMed=30894373

Origin% genome
African75.55
Native American0.48
East Asian, North4.1
East Asian, South0
South Asian0
European, North7
European, South12.87
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6949 (SF763)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
STR profile Source(s): DepMap

Markers:
AmelogeninX
CSF1PO9
D3S135815
D5S81812
D7S82011,12
D8S117913,14
D13S31710,12
D16S53910
D18S5116
D21S1127,30
FGA22
Penta D11,12
Penta E5,13
TH018,9
TPOX10,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=25984343; DOI=10.1038/sdata.2014.35
Cowley G.S., Weir B.A., Vazquez F., Tamayo P., Scott J.A., Rusin S., East-Seletsky A., Ali L.D., Gerath W.F.J., Pantel S.E., Lizotte P.H., Jiang G.-Z., Hsiao J., Tsherniak A., Dwinell E., Aoyama S., Okamoto M., Harrington W., Gelfand E.T., Green T.M., Tomko M.J., Gopal S., Wong T.C., Li H.-B., Howell S., Stransky N., Liefeld T., Jang D., Bistline J., Meyers B.H., Armstrong S.A., Anderson K.C., Stegmaier K., Reich M., Pellman D., Boehm J.S., Mesirov J.P., Golub T.R., Root D.E., Hahn W.C.
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Sci. Data 1:140035-140035(2014)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line databases/resources Cell_Model_Passport; SIDM01351
DepMap; ACH-000887
Biological sample resources BioSample; SAMN10988399
Chemistry resources PharmacoDB; SF172_1365_2019
Encyclopedic resources Wikidata; Q54952895
Polymorphism and mutation databases Cosmic; 2516034
Progenetix; CVCL_V613
Entry history
Entry creation16-Apr-2014
Last entry update21-Mar-2023
Version number14