Cellosaurus logo
expasy logo

Cellosaurus XP20BE (CVCL_V577)

[Text version]
Cell line name XP20BE
Synonyms Xeroderma Pigmentosum 20 BEthesda; AG08803
Accession CVCL_V577
Resource Identification Initiative To cite this cell line use: XP20BE (RRID:CVCL_V577)
Comments Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:3437; ERCC5; Simple; p.Glu11Ter (c.31G>T); Zygosity=Heterozygous (from autologous cell line XP20BE).
Disease Xeroderma pigmentosum-Cockayne syndrome complex (NCIt: C156031)
Xeroderma pigmentosum-Cockayne syndrome complex (ORDO: Orphanet_220295)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_V576 ! XP20BE LCL
Sex of cell Male
Age at sampling 1Y5M
Category Finite cell line
Publications

CLPUB00597
National Institute on Aging
1994 catalog of cell lines. NIA Aging Cell Repository.
(In misc. document) Institute for Medical Research (Camden, N.J.); pp.1-351; National Institutes of Health; Bethesda; USA (1994)

PubMed=8823375; DOI=10.1111/1523-1747.ep12584287
Shin-ichi Moriwaki, Miria Stefanini, Alan R. Lehmann, Jan Hendrik Jozef Hoeijmakers, Jay H. Robbins, Isabelle Rapin, Elena Botta, Bianca Tanganelli, Wim Vermeulen, Bernard C. Broughton, Kenneth H. Kraemer;
DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and Cockayne syndrome resemble xeroderma pigmentosum cells.
J. Invest. Dermatol. 107:647-653(1996)

PubMed=9447232; DOI=10.1016/S0921-8777(97)00031-1
Richard T. Okinaka, Ana V. Perez-Castro, Anthony Sena, Kevin Laubscher, Gary F. Strniste, Min S. Park, Rudy Hernandez, Mark A. MacInnes, Kenneth H. Kraemer;
Heritable genetic alterations in a xeroderma pigmentosum group G/Cockayne syndrome pedigree.
Mutat. Res. 385:107-114(1997)

PubMed=11841555; DOI=10.1046/j.0022-202x.2001.01673.x
Philippe Lalle, Thierry Nouspikel, Angelos Constantinou, Fabrizio Thorel, Stuart Gordon Clarkson;
The founding members of xeroderma pigmentosum group G produce XPG protein with severely impaired endonuclease activity.
J. Invest. Dermatol. 118:344-351(2002)

PubMed=12060391; DOI=10.1046/j.1523-1747.2002.01782.x
Steffen Emmert, Hanoch Slor, David B. Busch, Sima Batko, Roberta B. Albert, Donna M. Coleman, Sikandar G. Khan, Bassam Abu-Libdeh, John Joseph DiGiovanna, Bari Bickel Cunningham, Myung-Moo Lee ...Show all 19 authors... , Jill Crollick, Hiroki Inui, Takahiro Ueda, Mohammad Hedayati, Lawrence Grossman, Tala Shahlavi, James Edward Cleaver, Kenneth H. Kraemer; Show fewer authors
Relationship of neurologic degeneration to genotype in three xeroderma pigmentosum group G patients.
J. Invest. Dermatol. 118:972-982(2002)

PubMed=15572672; DOI=10.1128/mcb.24.24.10670-10680.2004; PMCID=PMC533987
Fabrizio Thorel, Angelos Constantinou, Isabelle Dunand-Sauthier, Thierry Nouspikel, Philippe Lalle, Anja Raams, Nicolaas G.J. Jaspers, Wim Vermeulen, Mahmud K.K. Shivji, Richard Dean Wood, Stuart Gordon Clarkson;
Definition of a short region of XPG necessary for TFIIH interaction and stable recruitment to sites of UV damage.
Mol. Cell. Biol. 24:10670-10680(2004)

PubMed=18079351; DOI=10.1259/bjr/27072321
Colin Francis Arlett, Michael H.L. Green, Paul Bryan Rogers, Alan R. Lehmann, Piers N. Plowman;
Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts.
Br. J. Radiol. 81:51-58(2008)

PubMed=19179371; DOI=10.1093/nar/gkp023; PMCID=PMC2651789
Siripan Limsirichaikul, Atsuko Niimi, Heather Fawcett, Alan R. Lehmann, Shunichi Yamashita, Tomoo Ogi;
A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU).
Nucleic Acids Res. 37:e31.1-e31.10(2009)

Cross-references
Cell line collections (Providers) Coriell; AG08803
Cell line databases/resources CLO; CLO_0031381
Encyclopedic resources Wikidata; Q54742529
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number14