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Cellosaurus AT2BE (CVCL_V560)

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Cell line name AT2BE
Synonyms Ataxia Telangiectasia 2 BEthesda; Se Pan
Accession CVCL_V560
Resource Identification Initiative To cite this cell line use: AT2BE (RRID:CVCL_V560)
Comments Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Finite cell line
Publications

PubMed=865488; DOI=10.1016/0027-5107(77)90138-5
Joyce F. Remsen, Peter A. Cerutti;
Excision of gamma-ray induced thymine lesions by preparations from ataxia telangiectasia fibroblasts.
Mutat. Res. 43:139-145(1977)

PubMed=643622; DOI=10.1093/nar/5.3.951; PMCID=PMC342035
Urs Kuhnlein, Betty Lee, Edward E. Penhoet, Stuart M. Linn;
Xeroderma pigmentosum fibroblasts of the D group lack an apurinic DNA endonuclease species with a low apparent Km.
Nucleic Acids Res. 5:951-960(1978)

PubMed=7374661; DOI=10.1016/0027-5107(80)90164-5
John Bertram Little, John Nove, Ralph R. Weichselbaum;
Abnormal sensitivity of diploid skin fibroblasts from a family with Gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C.
Mutat. Res. 70:241-250(1980)

PubMed=7471105
Ralph R. Weichselbaum, John Nove, John Bertram Little;
X-ray sensitivity of fifty-three human diploid fibroblast cell strains from patients with characterized genetic disorders.
Cancer Res. 40:920-925(1980)

PubMed=6810166; DOI=10.1016/0027-5107(82)90299-8
Thomas R. Barfknecht, John Bertram Little;
Hypersensitivity of ataxia telangiectasia skin fibroblasts to DNA alkylating agents.
Mutat. Res. 94:369-382(1982)

PubMed=2973075; DOI=10.2307/3577479
Bernard Fertil, Patrick J. Deschavanne, Danielle Debieu, Edmond-Philippe Malaise;
Correlation between PLD repair capacity and the survival curve of human fibroblasts in exponential growth phase: analysis in terms of several parameters.
Radiat. Res. 116:74-88(1988)

PubMed=3337113; PMCID=PMC1715319
Nicolaas G.J. Jaspers, Rob Desire F.M. Taalman, Carla C. Baan;
Patients with an inherited syndrome characterized by immunodeficiency, microcephaly, and chromosomal instability: genetic relationship to ataxia telangiectasia.
Am. J. Hum. Genet. 42:66-73(1988)

PubMed=9650596; DOI=10.2307/3579639
Louise Enns, Randy D.C. Barley, Malcolm C. Paterson, Razmik Mirzayans;
Radiosensitivity in ataxia telangiectasia fibroblasts is not associated with deregulated apoptosis.
Radiat. Res. 150:11-16(1998)

Cross-references
Cell line collections (Providers) ATCC; CRL-1343 - Discontinued
Encyclopedic resources Wikidata; Q54750862
Entry history
Entry creation16-Apr-2014
Last entry update10-Apr-2025
Version number14