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Cellosaurus KFr13 (CVCL_V534)

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Cell line name KFr13
Synonyms KFr
Accession CVCL_V534
Resource Identification Initiative To cite this cell line use: KFr13 (RRID:CVCL_V534)
Comments Population: Japanese.
Doubling time: 24.8 hours (Note=In presence of 0.5 mug cisplatin/ml), 27.2 hours (Note=In presence of 1 mug cisplatin/ml) (PubMed=3467111).
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_V533 (KF28)
Children:
CVCL_V535 (KFr13Tx)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=3467111; DOI=10.1093/jnci/77.6.1181
Yoshihiro Kikuchi, Munenori Miyauchi, Isao Kizawa, Keibun Oomori, Koichi Kato;
Establishment of a cisplatin-resistant human ovarian cancer cell line.
J. Natl. Cancer Inst. 77:1181-1185(1986)

PubMed=10741911; DOI=10.1007/s004320050027
Kenji Yamamoto, Yoshihiro Kikuchi, Kazuya Kudoh, Ichiro Nagata;
Modulation of cisplatin sensitivity by taxol in cisplatin-sensitive and -resistant human ovarian carcinoma cell lines.
J. Cancer Res. Clin. Oncol. 126:168-172(2000)

PubMed=11185891; DOI=10.1093/jjco/hyd116
Kenji Yamamoto, Yoshihiro Kikuchi, Kazuya Kudoh, Junko Hirata, Tsunekazu Kita, Ichiro Nagata;
Treatment with paclitaxel alone rather than combination with paclitaxel and cisplatin may be selective for cisplatin-resistant ovarian carcinoma.
Jpn. J. Clin. Oncol. 30:446-449(2000)

PubMed=17671176; DOI=10.1158/0008-5472.CAN-06-4567
Ryoko Kikuchi, Hitoshi Tsuda, Yae Kanai, Takahiro Kasamatsu, Kazuo Sengoku, Setsuo Hirohashi, Johji Inazawa, Issei Imoto;
Promoter hypermethylation contributes to frequent inactivation of a putative conditional tumor suppressor gene connective tissue growth factor in ovarian cancer.
Cancer Res. 67:7095-7105(2007)

PubMed=18319717; DOI=10.1038/sj.bjc.6604279; PMCID=PMC2275483
Tomoko Goto, Masashi Takano, Junko Hirata, Hitoshi Tsuda;
The involvement of FOXO1 in cytotoxic stress and drug-resistance induced by paclitaxel in ovarian cancers.
Br. J. Cancer 98:1068-1075(2008)

PubMed=18483383; DOI=10.1158/1078-0432.CCR-07-4358
Masako Ishibashi, Kentaro Nakayama, Shamima Yeasmin, Atsuko Katagiri, Kouji Iida, Naomi Nakayama, Manabu Fukumoto, Kohji Miyazaki;
A BTB/POZ gene, NAC-1, a tumor recurrence-associated gene, as a potential target for taxol resistance in ovarian cancer.
Clin. Cancer Res. 14:3149-3155(2008)

Cross-references
Cell line databases/resources CGH-DB; 327-2
CGH-DB; 349-3
Encyclopedic resources Wikidata; Q54899827
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number9