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Cellosaurus KYMM-2 (CVCL_UZ51)

[Text version]
Cell line name KYMM-2
Accession CVCL_UZ51
Resource Identification Initiative To cite this cell line use: KYMM-2 (RRID:CVCL_UZ51)
Comments Population: Japanese.
Characteristics: Produces IgG kappa (PubMed=22766978).
Characteristics: Compared to the autologous cell line KYMM-1, has a 5-fold higher expression of SDC1/CD138 (PubMed=22766978).
Miscellaneous: STR profile from personal communication of Hata, Hiroyuki.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_UZ50 ! KYMM-1
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11,13
D5S81811,12
D7S82011
D13S3178
D16S5399
D21S1130
TH019
TPOX11
vWA14

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Publications

PubMed=22766978; DOI=10.3892/ijo.2012.1545; PMCID=PMC3582943
Yawara Kawano, Shiho Fujiwara, Naoko Wada, Mikiko Izaki, Hiromichi Yuki, Yutaka Okuno, Kenichi Iyama, Hiroshi Yamasaki, Akira Sakai, Hiroaki Mitsuya, Hiroyuki Hata;
Multiple myeloma cells expressing low levels of CD138 have an immature phenotype and reduced sensitivity to lenalidomide.
Int. J. Oncol. 41:876-884(2012)

Cross-references
Encyclopedic resources Wikidata; Q95980572
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number8