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Cellosaurus KYMM-2 (CVCL_UZ51)

[Text version]
Cell line name KYMM-2
Accession CVCL_UZ51
Resource Identification Initiative To cite this cell line use: KYMM-2 (RRID:CVCL_UZ51)
Comments Population: Japanese.
Characteristics: Produces IgG kappa (PubMed=22766978).
Characteristics: Compared to the autologous cell line KYMM-1, has a 5-fold higher expression of SDC1/CD138 (PubMed=22766978).
Miscellaneous: STR profile from personal communication of Hata, Hiroyuki.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_UZ50 ! KYMM-1
Sex of cell Female
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX
CSF1PO11,13
D5S81811,12
D7S82011
D13S3178
D16S5399
D21S1130
TH019
TPOX11
vWA14

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Publications

PubMed=22766978; DOI=10.3892/ijo.2012.1545; PMCID=PMC3582943
Kawano Y., Fujiwara S., Wada N., Izaki M., Yuki H., Okuno Y., Iyama K., Yamasaki H., Sakai A., Mitsuya H., Hata H.
Multiple myeloma cells expressing low levels of CD138 have an immature phenotype and reduced sensitivity to lenalidomide.
Int. J. Oncol. 41:876-884(2012)

Cross-references
Encyclopedic resources Wikidata; Q95980572
Entry history
Entry creation25-Feb-2019
Last entry update10-Sep-2024
Version number7