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Cellosaurus HBl-10U/E6E7 (CVCL_UZ49)

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Cell line name HBl-10U/E6E7
Accession CVCL_UZ49
Resource Identification Initiative To cite this cell line use: HBl-10U/E6E7 (RRID:CVCL_UZ49)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Fetal urinary bladder; UBERON=UBERON_0001255.
Cell type: Urothelial cell; CL=CL_0000731.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_UZ47 (HBl-10U)
Sex of cell Sex unspecified
Age at sampling 20FW
Category Transformed cell line
Publications

PubMed=19489101; DOI=10.1002/stem.64; PMCID=PMC2733375
Sally Dabelsteen, Paula Hercule, Patricia Barron, Meghan Rice, Gregory Dorsainville, James George Rheinwald;
Epithelial cells derived from human embryonic stem cells display p16INK4A senescence, hypermotility, and differentiation properties shared by many P63+ somatic cell types.
Stem Cells 27:1388-1399(2009)

Cross-references
Encyclopedic resources Wikidata; Q93980599
Entry history
Entry creation25-Feb-2019
Last entry update14-Aug-2025
Version number9