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Cellosaurus KL-5 (CVCL_UZ45)

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Cell line name KL-5
Synonyms KL5
Accession CVCL_UZ45
Resource Identification Initiative To cite this cell line use: KL-5 (RRID:CVCL_UZ45)
Comments Senescence: Senesces at 23 PDL (PubMed=19489101).
Derived from site: In situ; Eye, cornea, epithelium; UBERON=UBERON_0001772.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_UZ46 (KL-5/bmi1/TERT)
Sex of cell Female
Age at sampling 30Y
Category Finite cell line
Web pages Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
Publications

PubMed=19489101; DOI=10.1002/stem.64; PMCID=PMC2733375
Sally Dabelsteen, Paula Hercule, Patricia Barron, Meghan Rice, Gregory Dorsainville, James George Rheinwald;
Epithelial cells derived from human embryonic stem cells display p16INK4A senescence, hypermotility, and differentiation properties shared by many P63+ somatic cell types.
Stem Cells 27:1388-1399(2009)

Cross-references
Encyclopedic resources Wikidata; Q94340303
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number7