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Cellosaurus HM-3 [Human mesothelia] (CVCL_UZ40)

[Text version]
Cell line name HM-3 [Human mesothelia]
Synonyms HM3
Accession CVCL_UZ40
Resource Identification Initiative To cite this cell line use: HM-3 [Human mesothelia] (RRID:CVCL_UZ40)
Comments Senescence: Senesces at 43 PDL (PubMed=12077343).
Derived from site: In situ; Peritoneal effusion; UBERON=UBERON_0001268.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_UZ41 (HM-3/p53DD)CVCL_UZ42 (HM-3/TERT)
Sex of cell Female
Age at sampling 29Y
Category Finite cell line
Web pages Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
Publications

PubMed=9382953; DOI=10.1089/hum.1997.8.16-1867
Murphy J.-E., Rheinwald J.G.
Intraperitoneal injection of genetically modified, human mesothelial cells for systemic gene therapy.
Hum. Gene Ther. 8:1867-1879(1997)

PubMed=12077343; DOI=10.1128/mcb.22.14.5157-5172.2002; PMCID=PMC139780
Rheinwald J.G., Hahn W.C., Ramsey M.R., Wu J.Y., Guo Z.-Y., Tsao H., De Luca M., Catricala C., O'Toole K.M.
A two-stage, p16(INK4A)- and p53-dependent keratinocyte senescence mechanism that limits replicative potential independent of telomere status.
Mol. Cell. Biol. 22:5157-5172(2002)

Cross-references
Encyclopedic resources Wikidata; Q94212653
Entry history
Entry creation25-Feb-2019
Last entry update10-Apr-2025
Version number7