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Cellosaurus SLR20.A2 (CVCL_UY80)

[Text version]
Cell line name SLR20.A2
Accession CVCL_UY80
Resource Identification Initiative To cite this cell line use: SLR20.A2 (RRID:CVCL_UY80)
Comments Problematic cell line: Contaminated. Parent cell line (SLR20) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4931; HLA-A (Note=Allele A*02:01).
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_V606 (SLR20)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=19690146; DOI=10.1158/0008-5472.CAN-08-4511; PMCID=PMC2745213
Mayumi Kawabe, Maja Mandic, Jennifer L. Taylor, Cecilia A. Vasquez, Amy K. Wesa, Leonard M. Neckers, Walter J. Storkus;
Heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17- demethoxygeldanamycin enhances EphA2+ tumor cell recognition by specific CD8+ T cells.
Cancer Res. 69:6995-7003(2009)

Cross-references
Cell line databases/resources cancercelllines; CVCL_UY80
Encyclopedic resources Wikidata; Q98132689
Entry history
Entry creation25-Feb-2019
Last entry update19-Dec-2024
Version number11